Understanding Pathophysiology

Key differences between 6th and 5th editions

• Time lapse between current and previous publications: 5 years (2016 vs 2011).
• Huether's Understanding Pathophysiology was first published in 1995.
• The Sixth Ed. is organized in to 2 Parts and 42 chapters -- two chapters more than in the Fifth Ed.
• New material in the Sixth Edition:
• New Chapter 3 on epigenetic mechanisms of human diseases.
• Chapter 15:
• Types of seizure disorders.
• Amyotrophic lateral sclerosis (Lou Gehrig's).
• Chapter 17:
• Perinatal and childhood stroke.
• Seizures and epilepsy in children.
• Chapter 19: discussion on underactive thyroid disease (hypothyroidism).
• Chapter 29:
• Level of creatinine in the blood.
• Blood urea nitrogen.
• Chapter 30:
• Mechanism of kidney stone formation (nephrolithiasis).
• Fluid and electrolyte balance.
• Calcium and phosphate balance in the bones.
• Chapter 33: discussion on inappropriate production and secretion of milk (galactorrhea).
• Chapter 34: discussion on abnormally large breasts in males (gynecomastia).
• Chapter 39: discussion on pathophysiology of persistent fatigue (chronic fatigue syndrome).