Pathophysiology: The Biologic Basis for Disease in Adults and Children

Pathophysiology: The Biologic Basis for Disease in Adults and Children Author(s): Kathryn L. McCance, Sue E. Huether

Difference between 7th and 6th editions
Side by side comparison of table of contents helps to figure out the most significant changes.

Key differences between 7th and 6th editions

  • Period between current and previous publications: 4 years (2013 vs 2009).
  • McCance's Pathophysiology text was originally published in 1990.
  • Chapter 1 presents updated material on cellular organelles, the plasma membrane, cell signaling, and communication.
  • Chapter 2 presents updated material on agents of cell injury, oxidative stress, apoptosis, and aging.
  • New Chapter 6 "Epigenetics and Disease", covering:
    • Epigenetics and Development
    • Genomic Imprinting
    • Future Directions Unit III Mechanisms of Self-Defense
  • Chapters 7 and 8 provide fresh material on normal innate and adaptive immunity.
  • Chapter 9 presents updated material on alterations of immunity and inflammation.
  • Chapter 10 provides material on emerging infections.
  • Chapter 11 has been reorganized and updated. New topic "Neuroendocrine Regulation".
  • Chapter 16 presents new topic "Rapid Eye Movement Sleep", updated content on chronic pain syndromes and classification of sleep disorders.
  • Chapter 17 presents updated material on alterations in consciousness, memory, delirium syndromes, and dementia. New information about Parkinson disease and amyotrophic lateral sclerosis.
  • Chapter 20 presents new topic "Epilepsy".
  • Chapter 22 on alterations of hormonal regulation has been extensively updated.
  • Former Sixth edition's chapter "Alterations of the Reproductive Systems" now is presented in two separate chapters 24 "Alterations of the Female Reproductive System" and 25 "Alterations of the Male Reproductive System".
  • Chapter 29 provides updated material on alterations of leukocyte, lymphoid, and hemostatic function.
  • Chapter 31 has been extensively rewritten.
  • Chapter 32 presents considerably updated material on atherosclerosis, endothelial injury and dysfunction, coronary artery disease, myocardial infarction, and heart failure.
  • Chapter 35 has new content on Viral Pneumonia.
  • Chapter 36 has been significantly updatedand and presents separate sub-sections on many pulmonary disorders, including Upper Airway Obstruction, Respiratory Distress Syndrome of the Newborn, Bronchopulmonary, Dysplasia Respiratory Tract Infections, Aspiration Pneumonitis, Bronchiolitis Obliterans, Asthma, Acute Lung Injury, and Cystic Fibrosis.
  • Chapter 39 provides new material on urinary tract infection, glomerulonephritis, and renal failure in children.
  • Chapter 42 provides new material on gluten-sensitive enteropathy, necrotizing enterocolitis, bowel obstruction, infections of the intestine,and liver disease in children.
  • Chapters 48 and 49 on shock, multiple organ dysfunction syndrome, and burns have been significantly updated and reorganized.
7th Edition of
Pathophysiology: The Biologic Basis for Disease in Adults and Children
eBook, 1840 pages
eBook ISBN: 9780323293754
Published by: Mosby, December 18, 2013
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$134.40
Hardcover, 1840 pages
ISBN-10: 0323088546
ISBN-13: 9780323088541
Published by: Mosby, December 27, 2013
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$115.82
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6th Edition of
Pathophysiology: The Biologic Basis for Disease in Adults and Children
Hardcover, 1864 pages
ISBN-10: 0323065848
ISBN-13: 9780323065849
Published by: Mosby, December 03, 2009
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$116.30
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$17.33 due: Mar 11
$16.42 due: Feb 09
Text and E-Book Package
Hardcover, 1838 pages
ISBN-10: 032306583X
ISBN-13: 9780323065832
Published by: Mosby, December 15, 2009
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From: $928.70
5th Edition of
Pathophysiology: The Biologic Basis for Disease in Adults And Children
Hardcover, 1744 pages
ISBN-10: 0323035078
ISBN-13: 9780323035071
Published by: Mosby, November 18, 2005
Book StoreNewUsedRent
$26.88
From: $0.01
From: $72.08 $10.24 due: Jun 04
$9.73 due: Mar 11
$9.22 due: Feb 09

Saving advice

Hardcover
  • Used 7th edition can save you $36.83 over the new one.
  • Used previous 6th edition costs $74.89 less than the used 7th.



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