Genetics: From Genes to Genomes

Genetics: From Genes to Genomes Author(s): Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro

Difference between 5th and 4th editions
Side by side comparison of table of contents helps to figure out the most significant changes.

Key differences between 5th and 4th editions

  • Period between previous and current publications: 4 years (2014 vs 2010).
  • Hartwell's Genetics text was originally published in 1999.
  • The content in the 5e textbook has been greatly updated and modernized, includes many new Fast Forward boxes, examples, and end-of-chapter problems.
  • Chapter 4: Discussion on sex chromosomes and mechanisms of sex determination in humans.
  • Chapter 6: Additional material on gene conversion process and molecular mechanism for genetic recombination.
  • Chapter 8:
    • Sydney Brenner's stop codon (or termination codon) experiments.
    • 21st and 22nd amino acids.
  • Chapter 9 covers new scientific instruments and methods, including bioinformatics, automated DNA sequencing.
  • Chapter 10: Up-to-date information on positional cloning, single nucleotide polymorphism detection by polymerase chain reaction methods, DNA fingerprinting, DNA microarray analysis.
  • Chapter 11:
    • Material on nucleosome reassembly following DNA replication.
    • Up-to-date additional material on histone tail modifications, mechanism of X chromosome inactivation.
  • Chapter 12:
    • Discussion about Barbara McClintock's discovery of "jumping genes" or or transposons.
    • Modern cytogenetic methods for analyzing ploidy and chromosomal rearrangement.
  • Chapter 14:
    • Carl Correns's study demonstrating maternal inheritance of chloroplast.
    • Mitochondrial DNA replacement therapy .
  • Chapter 15:
    • Trans-acting and Cis-acting RNAs.
    • Example: quorum sensing in Vibrio fischeri, a marine bioluminescent bacterium.
  • Completely new Chapter 17 on techniques for genome manipulation in Eukaryotes.
  • Chapter 18: Methods to determine genes that cause a mutant phenotype.
  • Chapter 20:
    • Section on Hardy-Weinberg principle of equilibrium.
    • Section on Y-DNA and mtDNA genetic ancestry testing.
  • Completely new Chapter 21 on complex trait genetics.
5th Edition of
Genetics: From Genes to Genomes
digital eBook, 816 pages
eBook ISBN: 9780077515096
Published by: McGraw-Hill Higher Education, September 05, 2014
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Hardcover, 816 pages
ISBN-10: 0073525316
ISBN-13: 9780073525310
Published by: McGraw-Hill Education, September 05, 2014
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Hardcover
ISBN-10: 1259668622
ISBN-13: 9781259668623
Published by: McGraw-Hill Education, March 10, 2015
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Loose Leaf
ISBN-10: 1259668630
ISBN-13: 9781259668630
Published by: McGraw-Hill Education, March 10, 2015
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International edition
Paperback
ISBN-10: 1259095541
ISBN-13: 9781259095542
Published by: McGraw Hill Higher Education, January 21, 2017
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4th Edition of
Genetics: From Genes to Genomes
Hardcover, 816 pages
ISBN-10: 007352526X
ISBN-13: 9780073525266
Published by: McGraw-Hill Education, September 14, 2010
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$40.28
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From: $8.52 $76.44 due: Mar 30
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$4.99 due: Dec 08
3rd Edition of
Genetics: From Genes to Genomes
Hardcover, 960 pages
ISBN-10: 0073227382
ISBN-13: 9780073227382
Published by: McGraw-Hill Science/Engineering/Math, October 09, 2006
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$27.15
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From: $87.91

Saving advice

Hardcover
  • Used 5th edition can save you $56.88 over the new one.
  • Used previous 4th edition costs $48.06 less than the used 5th.



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