A Microscale Approach to Organic Laboratory Techniques

Key differences between 5th and 4th editions

• Time lapse between current and previous publications: 6 years (2012 vs 2006).
• The book was first published in 1991.
• Two new Green Chemistry experiments involve techniques such as solid phase extraction and the use of a microwave reaction system.
• In two experiments, chiral gas chromatography is now included in the analysis of the products obtained.
• New experiments:
• 2 "Solubility" Part F. Nanotechnology Demonstration
• 27 "Biodiesel" covers biodiesels from coconut oil and other oils, analysis of diodiesel, and includes new essay on Biofuels.
• 31 Oxidation of Borneol to Camphor (new green procedure)
• 34 "Sonogashira Coupling of Iodosubstituted Aromatic Compounds with Alkynes"
• 35 "Grubbs-Catalyzed Metathesis of Eugenol with 1,4-Butanediol to Prepare a Natural Product"
• 44 N,N-diethyl-meta-toluamide (DEET) (new method)
• 48 "Diels-Alder Reaction with Anthracene-9-methanol"
• 55 "Competing Nucleophiles in SN1 and SN2 Reactions"
• 56 Friedel–Crafts alkylation (more substrates)
• 59 "Synthesis of Naproxen (Aleve®) by Palladium Catalysis"
• 62 "Green Epoxidation of Chalcones"
• 63 "Cyclopropanation of Chalcones."
• New method of obtaining boiling points and monitoring distillations using a temperature probe with one of the Vernier devices or a digital thermometer has been introduced.